About Platform
A game-changer in the realm of precision therapeutics, DOLOReS is our proprietary end-to-end human drug target identification and validation platform. Leveraging a comprehensive database built on transcriptomic and proteomic sequencing of human sensory tissue, DOLOReS is designed to expedite and de-risk therapeutic R&D and drive medical innovation to an unprecedented extent. Doloromics aims to reduce human suffering through precision medicine and reshape the future of disease management.
A comprehensive human-first target identification and validation platform
Neuro-Immune Cartography
Comprehensive next generation sequencing datasets to investigate the biology of the human Dorsal Root Ganglion (DRG) and spinal cord across health and disease.
Mechanism Focused Algorithms
A cutting-edge computational approach using human-first data, tissue profiling, and AI tools to find the mechanistic drivers of imbalance between the nervous system and immune system which lead to the persistence of disease.
In Vitro & Ex Vivo Modeling
Proprietary, Next Generation iPSC-derived sensory neurons and ex vivo human DRG tissue explants are utilized to recreate disease microenvironments and validate drug candidates.
Informed Clinical Translatability
Our platform focuses on human data and human disease mechanisms to treat underserved patient cohorts.
Use Cases
